Expression and regulation of nampt in human islets.

Nicotinamide phosphoribosyltransferase (Nampt) is a rate-limiting enzyme in the mammalian NAD+ biosynthesis of a salvage pathway and exists in 2 known forms, intracellular Nampt (iNampt) and a secreted form, extracellular Nampt (eNampt).eNampt can generate an intermediate product, nicotinamide mononucleotide (NMN), which has been reported to suppor

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Confound modelling in UK Biobank brain imaging

Dealing with confounds is an essential step in large cohort studies to address problems Collections such as unexplained variance and spurious correlations.UK Biobank is a powerful resource for studying associations between imaging and non-imaging measures such as lifestyle factors and health outcomes, in part because of the large subject numbers.Ho

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